[1]赵佐兴.五虎汤合葶苈大枣泻肺汤加减治疗新生儿支原体肺炎痰热闭肺证40例疗效观察[J].中医儿科杂志,2015,(03):18-21.
 ZHAO Zuoxing.Clinical curative effect of treatment with Wuhu Decoction combined with modified Tingli Dazao Xiefei Decoction treating neonatal mycoplasma pneumonia with phlegm heat obstructing lung syndrome[J].Journal of Pediatrics of Traditional Chinese Medicine,2015,(03):18-21.
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五虎汤合葶苈大枣泻肺汤加减治疗新生儿支原体肺炎痰热闭肺证40例疗效观察()
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《中医儿科杂志》[ISSN:/CN:62-1176/R]

卷:
期数:
2015年03期
页码:
18-21
栏目:
临床研究与报道
出版日期:
2015-05-25

文章信息/Info

Title:
Clinical curative effect of treatment with Wuhu Decoction combined with modified Tingli Dazao Xiefei Decoction treating neonatal mycoplasma pneumonia with phlegm heat obstructing lung syndrome
作者:
赵佐兴
桐庐县妇幼保健院儿科, 浙江 桐庐 311500
Author(s):
ZHAO Zuoxing
Pediatrics Department of Maternity and Child Care Center of Tonglu County, Tonglu, Zhejiang, 311500, China
关键词:
五虎汤葶苈大枣泻肺汤新生儿支原体肺炎
Keywords:
Wuhu DecoctionTingli Dazao Xiefei Decoctionneonatemycoplasma pneumonia
分类号:
R256.1
摘要:
目的 探讨五虎汤合葶苈大枣泻肺汤加减辨证治疗新生儿支原体肺炎痰热闭肺证的临床疗效及对相关细胞因子的影响。方法 选择我院收治的新生儿支原体肺炎痰热闭肺证患儿80例,随机分为治疗组和对照组各40例。对照组给予常规治疗,治疗组在常规治疗基础上给予五虎汤合葶苈大枣泻肺汤加减辨证治疗,观察并记录2组患儿的退热时间、肺部啰音消失时间以及住院时间,并于治疗7 d后对临床疗效以及相关细胞因子的变化进行统计分析。结果 治疗组患儿退热时间、肺部啰音消失时间及住院时间均明显短于对照组,差异均有统计意义(P<0.05);治疗组总有效率明显高于对照组,差异有统计意义(P<0.05);治疗7 d后,2组患儿血清IL-6,IL-8和TNF-α水平均较治疗前明显降低(P<0.01),且治疗组改善程度更为明显,差异均有高度统计意义(P<0.01)。结论 五虎汤合葶苈大枣泻肺汤辨证治疗新生儿支原体肺炎痰热闭肺证不仅有助于改善临床症状,提高临床疗效,而且对于提高患儿的免疫功能也具有重要作用。
Abstract:
Objective To investigate the clinical curative effect and influence on related cytokines of syndrome deferential treatment with Wuhu Decoction combined with modified Tingli Dazao Xiefei Decoction treating neonatal mycoplasma pneumonia(phlegm-heat obstructing lung syndrome). Methods 40 cases of patients in our hospital with neonatal mycoplasma pneumonia with phlegm heat obstructing lung syndrome were randomly divided into a treatment group and a control group. The control group were given conventional treatment while the treatment group were given deferential treatment with Wuhu Decoction combined with modified Tingli Dazao Xiefei Decoction on the basis of conventional treatment.Observed and recorded the antifebrile time,lung rale disappear time and hospital stay time of the two groups and evaluated the clinical curative effect and the change of related cytokines after treatment for 7 days.Results The antifebrile time, lung rale disappear time and hospital stay time of the treatment group were significantly shorter than those in the control group, and the difference was statistically significant(P<0.05).The overall response rate of the treatment group was significantly higher than that of the control group, and the difference had statistical significance (P<0.05). After treatment for 7 days,the serum IL-6, IL-8 and TNF-α level of the children in the two groups were significantly lower than those before treatment(P<0.01),and the treatment group improved better than the control group, the difference had statistical significance(P<0.01).Conclusion When treating neonatal mycoplasma pneumonia with phlegm heat obstructing lung syndrome, deferential treatment with Wuhu Decoction combined with modified Tingli Dazao Xiefei Decoction not only can improve the clinical symptoms and clinical curative effect,but also can improve children’s immune function.

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备注/Memo

备注/Memo:
收稿日期:2014-9-25
作者简介:赵佐兴(1969-),男,主治医师,医学学士,主要从事新生儿相关疾病的诊断和治疗工作。
更新日期/Last Update: 1900-01-01