[1]何秀娇.宁血汤佐治重度儿童原发性免疫性血小板减少症25例疗效观察[J].中医儿科杂志,2015,(03):37-40.
 HE Xiujiao.Clinical analysis of Ningxue Tang as combination therapy for severe primary immune thrombocytopenia in children[J].Journal of Pediatrics of Traditional Chinese Medicine,2015,(03):37-40.
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宁血汤佐治重度儿童原发性免疫性血小板减少症25例疗效观察()
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《中医儿科杂志》[ISSN:/CN:62-1176/R]

卷:
期数:
2015年03期
页码:
37-40
栏目:
临床研究与报道
出版日期:
2015-05-25

文章信息/Info

Title:
Clinical analysis of Ningxue Tang as combination therapy for severe primary immune thrombocytopenia in children
作者:
何秀娇
茂名市中医院儿科, 广东 茂名 525000
Author(s):
HE Xiujiao
Pediatric Department of TCM Hospital of Maoming City, Maoming, Guangdong, 525000, China
关键词:
宁血汤儿童原发性免疫性血小板减少症
Keywords:
Ningxue Tangchildrenprimary immune thrombocytopenia
分类号:
R593.1
摘要:
目的 探讨在激素常规治疗基础上联合宁血汤治疗重度儿童原发性免疫性血小板减少症(ITP)的临床疗效。方法 将本院收治的50例重度ITP患儿随机分为治疗组和对照组,2组均给予西医常规治疗,治疗组患儿在此基础上给予自制宁血汤口服,每日1剂。比较治疗1月后2组的总有效率、止血时间、血小板计数恢复正常时间、住院时间等。结果 治疗组总有效率为88.0%,对照组为72.0%,2组比较差异有统计意义(P<0.05)。治疗组止血时间、血小板计数恢复正常时间、住院时间等指标均短于对照组(P<0.05)。随访1年,治疗组1例因上呼吸道感染复发,症状较轻,经抗感染及口服宁血汤后血小板自行上升至正常;对照组5例因上呼吸道感染复发,3例较轻,经抗感染及口服宁血汤后血小板自行上升至正常,2例因血小板<30×109/L住院。结论 激素常规联合宁血汤治疗能够显著提高ITP患儿的临床疗效,缩短激素用药时间,减少不良反应,显著降低复发率。
Abstract:
Objective To investigate the clinical efficacy of Ningxue Tang treating severe primary immune thrombocytopenia in children based on hormone conventional therapy.Methods 50 cases of children with severe primary immune thrombocytopenia were randomly divided into treatment group and control group. All children were given conventional treatment. The treatment group were additionally given home-made Ningxue Tang, a dose each day. The curative efficacy, blood stopping time, blood platelet count and hospital stays were compared. Results The overall response of the treatment group were 88.0%, and that of the control group was 72.0%, and the difference of the two groups was statistically significant (P<0.05). The blood stopping time, time of platelet count return to normal and hospital stays of the treatment group were significantly shorter than those of the control group (P<0.05). After follow-up of 1 year, 1 case in the treatment group reoccurred because of upper respiratory tract infection, with light symptoms. After anti-infection and oral Ningxue Tang, the blood platelets rose to normal. 5 cases in the control group reoccurred because of upper respiratory tract infection, 3 cases with lighter symptoms. After anti-infection and oral Ningxue Tang, the blood platelets rose to normal. 2 cases were sent to hospital due to platelet < 30×109/L. Conclusion Ningxue Tang treating severe primary immune thrombocytopenia in children based on hormone conventional therapy can significantly improve the clinical curative effect, shortening the time of hormone drugs, reducing side effects and significantly reducing the recurrence rate.

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备注/Memo

备注/Memo:
收稿日期:2014-9-16
基金项目:茂名市科研立项项目(0013462140711014)。
作者简介:何秀娇(1981-),女,主治中医师,医学学士,主要从事中医儿科临床工作。
更新日期/Last Update: 1900-01-01