[1]陈双.自拟益气脱敏汤联合西药治疗小儿变应性鼻炎53例临床观察[J].中医儿科杂志,2019,15(02):38-41.[doi:10.16840/j.issn1673-4297.2019.02.12]
 CHEN Shuang.Clinical observation on 53 cases of children with allergic rhinitis treated by self-made Yiqi Tuomin Tang (益气脱敏汤) combined with Western medicine[J].Journal of Pediatrics of Traditional Chinese Medicine,2019,15(02):38-41.[doi:10.16840/j.issn1673-4297.2019.02.12]
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自拟益气脱敏汤联合西药治疗小儿变应性鼻炎53例临床观察
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《中医儿科杂志》[ISSN:/CN:62-1176/R]

卷:
15
期数:
2019年02期
页码:
38-41
栏目:
临床研究与报道
出版日期:
2019-03-25

文章信息/Info

Title:
Clinical observation on 53 cases of children with allergic rhinitis treated by self-made Yiqi Tuomin Tang (益气脱敏汤) combined with Western medicine
作者:
陈双
台州恩泽医疗中心路桥, 医院儿科, 浙江, 台州 318050
Author(s):
CHEN Shuang
Department of Pediatrics, Luqiao Hospital of Taizhou Enze Medical Center(Group), Taizhou, Zhejiang, 318050, China
关键词:
变应性鼻炎小儿自拟益气脱敏汤氯雷他定片临床观察
Keywords:
allergic rhinitischildrenself-made Yiqi Tuomin Tang (益气脱敏汤)loratadine tabletsclinical observation
分类号:
R276.1
DOI:
10.16840/j.issn1673-4297.2019.02.12
摘要:
目的 观察自拟益气脱敏汤联合西药治疗小儿变应性鼻炎的临床疗效。方法 选取2016年1月至2017年6月在我科接受治疗的106例变应性鼻炎患儿,随机分为对照组和治疗组,各53例。对照组给予氯雷他定片口服治疗,治疗组在对照组治疗方法的基础上加用自拟益气脱敏汤治疗。2组均连续用药21 d后统计疗效。结果 治疗组总有效率为92.45%,显著高于对照组的71.70%,2组比较,差异有统计学意义(P<0.05)。治疗后,2组打喷嚏、流涕、鼻塞、鼻痒评分均显著低于
Abstract:
Objective To observe the clinical efficacy of allergic rhinitis in children treated by self-made Yiqi Tuomin Tang (益气脱敏汤) combined with Western medicine.Methods Totally 106 cases of allergic rhinitis treated in our department from January 2016 to June 2017 were randomly divided into control group and treatment group,with 53 cases in each.The control group was given oral loratadine tablets,while the treatment group was given self-made Yiqi Tuomin Tang on the basis of the control group.The 2 groups were both given 21 days of continuous medication and then the clinical efficacy were kept by statistics.Results The total effective rate of the treatment group was 92.45%,which was significantly higher than 71.70% of the control group,there was statistically significant difference between the two groups (P<0.05).After treatment,the scores of sneeze,coryza,rhinobyon and rhinocnesmus of the two groups were all significantly lower than those before treatment (P<0.05),moreover,the decrease extent of the treatment group was more significant (P<0.05).After treatment in the two groups,the expression levels of the serum IgE and IL-17 significantly decreased,while that of IL-10 increased,the difference was statistically significant compared with the same group before treatment (P<0.05),moreover,the improvement extent of each index in the treatment group was superior to that in the control group (P<0.05).There was 1 case of fatigue in the treatment group and 1 case of drowsiness,fatigue and gastrointestinal discomfort in the control group,respectively,there was no statistically significant difference in the incidence of adverse reactions between the two groups (P>0.05).Conclusion Self-made Yiqi Tuomin Tang combined with Western medicine in the treatment of allergic rhinitis in children has satisfactory clinical efficacy,and it can markedly improve the main clinical symptoms with less adverse reactions,which deserves clinical promotion and application.

参考文献/References:

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备注/Memo

备注/Memo:
作者简介:陈双(1989-),男,住院医师,医学学士,主要从事儿科临床诊疗工作。
更新日期/Last Update: 1900-01-01