[1]唐中为,欧绪森.清热凉血方联合西药治疗儿童过敏性紫癜风热伤络型42例临床观察[J].中医儿科杂志,2019,15(02):64-67.[doi:10.16840/j.issn1673-4297.2019.02.19]
 TANG Zhongwei,OU Xusen.Clinical observation on 42 cases of Henoch-Schonlein purpura with impairment of collaterals due to wind-heat type in children treated by Qingre Liangxue Fang (清热凉血方)combined with Western medicine[J].Journal of Pediatrics of Traditional Chinese Medicine,2019,15(02):64-67.[doi:10.16840/j.issn1673-4297.2019.02.19]
点击复制

清热凉血方联合西药治疗儿童过敏性紫癜风热伤络型42例临床观察
分享到:

《中医儿科杂志》[ISSN:/CN:62-1176/R]

卷:
15
期数:
2019年02期
页码:
64-67
栏目:
临床研究与报道
出版日期:
2019-09-25

文章信息/Info

Title:
Clinical observation on 42 cases of Henoch-Schonlein purpura with impairment of collaterals due to wind-heat type in children treated by Qingre Liangxue Fang (清热凉血方)combined with Western medicine
作者:
唐中为1 欧绪森2
1. 象山县红十字台胞医院儿科, 浙江 象山 315731;
2. 象山县红十字台胞医院中医科, 浙江 象山 315731
Author(s):
TANG Zhongwei1 OU Xusen2
1. Department of Pediatrics, Xiangshan County Red Cross Taiwan Compatriots Hospital, Xiangshan, Zhejiang, 315731, China;
2. Department of TCM, Xiangshan County Red Cross Taiwan Compatriots Hospital, Xiangshan, Zhejiang, 315731, China
关键词:
过敏性紫癜儿童风热伤络型免疫功能临床观察
Keywords:
Henoch-Schonlein purpurachildrenimpairment of collaterals due to wind-heat typeimmunological functionclinical observation
分类号:
R593.1
DOI:
10.16840/j.issn1673-4297.2019.02.19
摘要:
目的 观察清热凉血方联合西药治疗儿童过敏性紫癜风热伤络型的临床疗效。方法 选取我院2015年1月至2017年2月收治的过敏性紫癜风热伤络型患儿84例,采用随机数字表法分为对照组和治疗组,各42例。对照组采用常规西药治疗,治疗组在对照组治疗方法的基础上联合中药清热凉血方治疗。治疗1月并随访2周后,比较2组的临床疗效、治疗前后免疫球蛋白水平变化及不良反应发生情况。结果 对照组总有效率为71.4%,治疗组为95.2%,2组比较,差异有统计学意义(P<0.0
Abstract:
Objective To observe the clinical efficacy of Qingre Liangxue Fang (清热凉血方) combined with Western medicine in the treatment of children of Henoch-Schonlein purpura with impairment of collaterals due to wind-heat type.Methods Eighty-four cases of Henoch-Schonlein purpura with impairment of collaterals due to wind-heat type admitted to our hospital from January 2015 to February 2017 were divided into control group and treatment group according to random number table,with 42 cases in each.The control group was treated with routine Western medicine,and the treatment group was combined with Qingre Liangxue Fang on the basis of the treatment of the control group.After treatment for 1 month and follow-up for 2 weeks,the clinical efficacy,the changes of immunoglobulin levels before and after treatment and the incidence of adverse reactions were compared between the two groups.Results The total effective rate of the control group was 71.4%,that of the treatment group was 95.2%,there was statistically significant difference between the two groups (P<0.01).Before treatment,the levels of IgA,IgG and IgM in both groups showed no significant difference (P>0.05),and they were comparable.After treatment,there was no significant change in IgM level in the two groups,and there was no statistically significant difference compared with the same group before treatment (P>0.05);the levels of IgA and IgG decreased significantly,the difference was statistically significant compared with the same group before treatment (P<0.05),moreover,the decrease in the treatment group was more significant (P<0.05).The total incidence of adverse reactions between the two groups showed no significant difference by statistics analysis (P>0.05).Conclusion Qingre Liangxue Fang combined with Western medicine in the treatment of Henoch-Schonlein purpura with impairment of collaterals due to wind-heat type in children has significant clinical efficacy,which can significantly improve immunological function of children patients with high security.It deserves clinical promotion and application.

参考文献/References:

[1] 石艳红,肖达民,张春红,等.联用中药清热解表方治疗儿童过敏性紫癜的效果及对患儿可溶性细胞间黏附因子-1的影响[J].广东医学,2016,37(8):1231-1233.
[2] 王妍炜,林志红,张蕾,等.中药熏蒸和耳穴压豆联合常规方案治疗小儿过敏性紫癜的临床观察[J].中国中西医结合杂志,2017,37(10):1264-1266.
[3] 胡亚美,江载芳.诸福棠实用儿科学[M].7版.北京:人民卫生出版社,2002:45-48.
[4] 李红文,张琼. 皮肤性病学[M].郑州:郑州大学出版社,2009:121-124.
[5] 江育仁,朱锦善.现代中医儿科学[M].上海:上海中医药大学出版社,2005:167-169.
[6] 张之南,沈悌.血液病诊断及疗效标准[M].北京:科学技术出版社,2007:76-79.

相似文献/References:

[1]路新强.中药保留灌肠联合序贯腹膜透析治疗儿童急性肾衰竭临床疗效观察[J].中医儿科杂志,2015,(04):58.
 LU Xinqiang.Clinical efficacy of TCM retention enema and sequential peritoneal dialysis on children with acute renal failure[J].Journal of Pediatrics of Traditional Chinese Medicine,2015,(02):58.
[2]朱大鹏.中西医治疗儿童腺样体肥大研究进展[J].中医儿科杂志,2015,(04):82.
 ZHU Dapeng.Research progress in treating infantile adenoidal hypertrophy with integrated western medicine and TCM[J].Journal of Pediatrics of Traditional Chinese Medicine,2015,(02):82.
[3]刘璐,叶芹,姚力.麻杏石甘汤联合小儿清热宣肺贴膏治疗急性支气管炎99例疗效观察[J].中医儿科杂志,2015,(02):19.
 LIU Lu,YE Qin,YAO Li.Curative effect analysis of Maxingshigan Decoction combined with Xiaoer Qingre Xuanfei Emplastrum treating 99 cases of acute bronchitis[J].Journal of Pediatrics of Traditional Chinese Medicine,2015,(02):19.
[4]张美菁,张喜莲,马融.银翘散在儿科临床中的应用及相关免疫炎症机制研究进展[J].中医儿科杂志,2015,(02):75.
 ZHANG Meijing,ZHANG Xilian,MA Rong.Application of Yinqiao Powder in pediatrics and progress of the related immune inflammation mechanisms[J].Journal of Pediatrics of Traditional Chinese Medicine,2015,(02):75.
[5]刘晔婷,曹志宏,熊光明,等.苏黄止咳胶囊治疗儿童感冒后咳嗽50例疗效观察[J].中医儿科杂志,2015,(01):26.
 LIU Yeting,CAO Zhihong,XIONG Guangming,et al.Effect observation of Suhuang Zhike Jiaonang in treating 50 cases of pediatric cough after cold[J].Journal of Pediatrics of Traditional Chinese Medicine,2015,(02):26.
[6]李卉.参附注射液在儿科临床应用举隅[J].中医儿科杂志,2015,(01):38.
 LI Hui.Shenfu Injection applied in the pediatric clinic[J].Journal of Pediatrics of Traditional Chinese Medicine,2015,(02):38.
[7]王忠民,王明闯,徐慧祥.易感颗粒治疗小儿反复呼吸道感染(发作期)临床研究[J].中医儿科杂志,2015,(03):8.
 WANG Zhongmin,WANG Mingchuang,XU Huixiang.The clinical effect of Yigan Keli in the treatment of recurrent respiratory tract infection of children (attack stage)[J].Journal of Pediatrics of Traditional Chinese Medicine,2015,(02):8.
[8]何秀娇.宁血汤佐治重度儿童原发性免疫性血小板减少症25例疗效观察[J].中医儿科杂志,2015,(03):37.
 HE Xiujiao.Clinical analysis of Ningxue Tang as combination therapy for severe primary immune thrombocytopenia in children[J].Journal of Pediatrics of Traditional Chinese Medicine,2015,(02):37.
[9]刘娟,梅向阳.理气暖胃止痛贴外敷治疗儿童功能性腹痛30例临床观察[J].中医儿科杂志,2015,(03):44.
 LIU Juan,MEI Xiangyang.Clinical efficacy of regulating qi warming stomach and relieving pain external pasting in the treatment of 30 cases of infantile functional abdominal pain[J].Journal of Pediatrics of Traditional Chinese Medicine,2015,(02):44.
[10]庞高峰,范桂红,朱迪卿,等.孟鲁司特钠联合平喘止咳贴治疗儿童咳嗽变异性哮喘60例疗效观察[J].中医儿科杂志,2015,(05):23.
 PANG Gaofeng,FAN Guihong,ZHU Diqing,et al.Observation of clinical effectiveness of Montelukast combined with Pingchuan Zhike Tie in the treatment of 60 children with cough variant asthma (CVA)[J].Journal of Pediatrics of Traditional Chinese Medicine,2015,(02):23.
[11]孔飞.从瘀论治小儿过敏性紫癜[J].中医儿科杂志,2008,(03):9.
 Kong Fei.Treat children allergic purpura from blood stasis[J].Journal of Pediatrics of Traditional Chinese Medicine,2008,(02):9.
[12]赵长江,袁斌.小儿哮喘病的中医医史文献研究[J].中医儿科杂志,2009,(01):53.
[13]李婉丽,宋国才,石淑华.儿童过敏性紫癜器官功能损害研究进展[J].中医儿科杂志,2009,(04):46.
[14]吴文先,祝伟,程艳波.水蛭治疗儿童过敏性紫癜临床疗效观察[J].中医儿科杂志,2011,(05):23.
 Wu Wenxian,Zhu Wei,Cheng Yanbo.Clinical effect observation of leeches in the treatment of children with allergic purpura[J].Journal of Pediatrics of Traditional Chinese Medicine,2011,(02):23.
[15]张立环.儿童过敏性紫癜的护理体会[J].中医儿科杂志,2012,(03):63.
 Zhang Lihuan.The nursing experience of pediatric Allergic Purpura patient[J].Journal of Pediatrics of Traditional Chinese Medicine,2012,(02):63.
[16]烟海丽.犀角地黄汤加味治疗过敏性紫癜40例临床观察[J].中医儿科杂志,2014,(03):42.
 Yan Haili.Clinical observation of Xijiaodihuang Decoction in treating allergic purpura in 40 cases[J].Journal of Pediatrics of Traditional Chinese Medicine,2014,(02):42.
[17]龚方彪,汪玲娟,何斌.中西医结合治疗儿童过敏性紫癜40例临床观察[J].中医儿科杂志,2017,(06):61.[doi:10.16840/j.issn1673-4297.2017.06.18]
 GONG Fangbiao,WANG Lingjuan,HE Bin.Clinical study on the combination of Chinese and Western medicine in treating 40 children with anaphylactoid purpura[J].Journal of Pediatrics of Traditional Chinese Medicine,2017,(02):61.[doi:10.16840/j.issn1673-4297.2017.06.18]
[18]马晓慧,罗晓明,陈小红.玉屏风散对过敏性紫癜患儿激素应用时间及免疫功能调节的影响[J].中医儿科杂志,2019,15(01):59.[doi:10.16840/j.issn1673-4297.2019.01.20]
 MA Xiaohui,LUO Xiaoming,CHEN Xiaohong.Effects of Yupingfeng San (玉屏风散) in hormone application time and immune regulation in children with Henoch-Schonlein purpura[J].Journal of Pediatrics of Traditional Chinese Medicine,2019,15(02):59.[doi:10.16840/j.issn1673-4297.2019.01.20]

备注/Memo

备注/Memo:
作者简介:唐中为(1980-),男,主治医师,医学学士,主要从事中西医结合儿科临床诊疗工作。
更新日期/Last Update: 1900-01-01