[1]张燕.针刺联合氟哌啶醇治疗小儿抽动秽语综合征35例临床观察[J].中医儿科杂志,2019,15(02):74-77.[doi:10.16840/j.issn1673-4297.2019.02.22]
 ZHANG Yan.Clinical observation on 35 cases of children with Gilles de la Tourette syndrome treated by acupuncture treatment combined with haloperidol[J].Journal of Pediatrics of Traditional Chinese Medicine,2019,15(02):74-77.[doi:10.16840/j.issn1673-4297.2019.02.22]
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针刺联合氟哌啶醇治疗小儿抽动秽语综合征35例临床观察
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《中医儿科杂志》[ISSN:/CN:62-1176/R]

卷:
15
期数:
2019年02期
页码:
74-77
栏目:
针灸推拿
出版日期:
2019-09-25

文章信息/Info

Title:
Clinical observation on 35 cases of children with Gilles de la Tourette syndrome treated by acupuncture treatment combined with haloperidol
作者:
张燕
海宁市中心医院儿科, 浙江 海宁 314008
Author(s):
ZHANG Yan
Department of Pediatrics, Haining Central Hospital, Haining, Zhejiang, 314008, China
关键词:
抽动秽语综合征小儿针刺氟哌啶醇多巴胺5-羟色胺临床观察
Keywords:
Gilles de la Tourette syndromechildrenacupuncturehaloperidoldopamine5-HTclinical observation
分类号:
R272.6
DOI:
10.16840/j.issn1673-4297.2019.02.22
摘要:
目的 观察针刺联合氟哌啶醇治疗小儿抽动秽语综合征的临床疗效。方法 选取2015年9月至2017年9月我院儿科收治的70例抽动秽语综合征患儿,采用随机数字表法分为对照组和治疗组,各35例。对照组口服氟哌啶醇治疗,治疗组在对照组治疗方法的基础上采用穴位针刺治疗,8周后统计2组的临床疗效。结果 治疗前2组运动性抽动和发声性抽动耶鲁综合抽动严重程度量表(YGTSS)评分比较,差异无统计学意义(P>0.05),具有可比性。治疗8周后,2组运动性抽动和发声性抽动
Abstract:
Objective To observe the clinical efficacy of acupuncture combined with haloperidol in the treatment of children with Gilles de la Tourette syndrome.Methods Seventy cases with Gilles de la Tourette syndrome treated in pediatrics department in our hospital from September 2015 to September 2017 were chosen and randomly divided into control group and treatment group according to the random number table,with 35 cases in each.The control group was given oral haloperidol,the treatment group was given acupoint acupuncture therapy on the basis of the control group.The clinical efficacy of the 2 groups were kept by statistics after treatment for 8 weeks.Results There was no significant difference in YGTSS scores of motor tics and vocal tics between the two groups before treatment (P>0.05),and they were comparable.After treatment for 8 weeks,YGTSS scores of motor tics and vocal tics in both groups were significantly lower than those in the same group before treatment (P<0.01),moreover,the decrease in the treatment group was more significant (P<0.05).The total effective rate of the control group was 71.43%,that of the treatment group was 94.29%,the difference was statistically significant between the two groups (P<0.05).Before treatment,the difference was not statistically significant in the plasma levels of dopamine (DA) and 5-HT between the two groups (P>0.05),and they were comparable;after treatment,the plasma levels of DA and 5-HT in the two groups both significantly decreased,the difference was statistically significant compared with the same group before treatment (P<0.01),moreover,the treatment group decreased more significantly (P<0.05).Conclusion The acupuncture combined with haloperidol in the treatment of children with Gilles de la Tourette syndrome has marked clinical efficacy,and it can effectively improve the YGTSS scores of motor tics and vocal tics,the levels of DA and 5-HT,which is worthy of clinical promotion.

参考文献/References:

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备注/Memo

备注/Memo:
作者简介:张燕(1983-),女,主治医师,医学学士,主要从事儿科临床诊疗工作。
更新日期/Last Update: 1900-01-01