[1]陆敏瑜.清肺解毒益气方辅助治疗小儿支原体肺炎合并心肌炎30例临床观察[J].中医儿科杂志,2019,15(03):32-35.[doi:10.16840/j.issn1673-4297.2019.03.11]
 LU Minyu.Clinical observation on Qingfei Jiedu Yiqi Fang (清肺解毒益气方) in adjuvant treatment of 30 cases of mycoplasma pneumoniae complicated with myocarditis in children[J].Journal of Pediatrics of Traditional Chinese Medicine,2019,15(03):32-35.[doi:10.16840/j.issn1673-4297.2019.03.11]
点击复制

清肺解毒益气方辅助治疗小儿支原体肺炎合并心肌炎30例临床观察
分享到:

《中医儿科杂志》[ISSN:/CN:62-1176/R]

卷:
15
期数:
2019年03期
页码:
32-35
栏目:
临床研究与报道
出版日期:
2019-05-25

文章信息/Info

Title:
Clinical observation on Qingfei Jiedu Yiqi Fang (清肺解毒益气方) in adjuvant treatment of 30 cases of mycoplasma pneumoniae complicated with myocarditis in children
作者:
陆敏瑜
湖州市南浔区人民医院儿科, 浙江 湖州 313009
Author(s):
LU Minyu
Department of Pediatrics, Nanxun District the People's Hospital of Huzhou, Huzhou, Zhejiang, 313009, China
关键词:
支原体肺炎心肌炎小儿清肺解毒益气方心肌酶谱临床观察
Keywords:
mycoplasma pneumoniaemyocarditischildrenQingfei Jiedu Yiqi Fang (清肺解毒益气方)myocardial enzyme spectrumclinical observation
分类号:
R256.1
DOI:
10.16840/j.issn1673-4297.2019.03.11
摘要:
目的 观察清肺解毒益气方辅助治疗小儿肺炎合并心肌炎的临床疗效。方法 选取2017年1月至2018年1月在湖州市南浔区人民医院儿科接受治疗的支原体肺炎合并心肌炎患儿共60例,按照随机数字表法分为治疗组和对照组,各30例。对照组给予西医支原体肺炎常规抗感染、营养心肌治疗,治疗组在对照组治疗方法的基础上联合清肺解毒益气方,治疗5 d后统计2组治疗前后心肌肌酸激酶(CK)及其同工酶(CK-MB)、天门冬氨酸氨基转移酶(AST)、乳酸脱氢酶(LDH)、α-羟丁酸脱氢酶(α-HBDH)水平以及临床疗效。结果 治疗前2组AST、LDH、α-HBDH、CK、CK-MB水平比较,差异无统计学意义(P>0.05),具有可比性。治疗后2组AST、LDH、α-HBDH、CK、CK-MB水平均显著下降,与同组治疗前比较,差异有统计学意义(P<0.05或P<0.01),且治疗组下降更显著(P<0.05)。对照组总有效率为73.33%,治疗组为96.67%,2组比较,差异有统计学意义(P<0.05)。结论 清肺解毒益气方辅助治疗小儿支原体肺炎合并心肌炎,能显著改善患儿心肌酶谱水平,临床疗效显著,值得临床推广应用。
Abstract:
Objective To observe the clinical efficacy of Qingfei Jiedu Yiqi Fang (清肺解毒益气方) in adjuvant treatment of mycoplasma pneumoniae complicated with myocarditis in children.Methods Sixty children with mycoplasma pneumonia complicated with myocarditis admitted to Nanxun District the People's Hospital from January 2017 to January 2018 were chosen and divided into control group and treatment group according to random number table method,with 30 cases in each.The control group was given routine anti-infection and nutritional myocardial therapy for mycoplasma pneumonia in Western medicine.The treatment group was given combined Qingfei Jiedu Yiqi Fang (清肺解毒益气方) on the basis of the control group.After treatment for 5 days,we kept statistics of the levels of myocardial creatine kinase (CK) and its isoenzyme (CK-MB) changes,glutamic aminotransferase (AST),lactate dehydrogenase (LDH) and alpha hydroxybutyrate dehydrogenase (α-HBDH) as well as the clinical efficacy of the 2 groups before and after treatment.Results Before treatment,there was no statistically significant difference in the levels of AST,LDH,α-HBDH, CK and CK-MB between the two groups (P>0.05),and they were comparable.After treatment, the levels of AST,LDH,α-HBDH, CK and CK-MB decreased significantly,the difference was statistically significant compared with the same group before treatment (P<0.05 or P<0.01),moreover,the treatment group decreased more significantly (P<0.05).The total effective rate of the control group was 73.33%,that of the treatment group was 96.67%,and the difference was statistically significant between the two group (P<0.05).Conclusion It can significantly improve the levels of myocardial enzyme spectrum of the children patients to use Qingfei Jiedu Yiqi Fang in adjuvant treatment of mycoplasma pneumoniae complicated with myocarditis in children,with significant clinical efficacy,which is worthy of clinical promotion and application.

参考文献/References:

[1] 陈嘉慧,印根权,余嘉璐,等.红霉素与阿奇霉素治疗小儿肺炎支原体肺炎的临床研究[J].中国临床药理学杂志,2015,31(8):587-589.
[2] 陈广道,梁少媛,冯柏潮.儿童支原体肺炎的临床表现和实验室检查及影像学特点分析[J].中国全科医学,2015,18(1):59-64.
[3] 中华医学会儿科学分会呼吸学组,《中华实用儿科临床杂志》编辑委员会.儿童支原体肺炎诊治专家共识(2015年版)[J].中华实用儿科临床杂志,2015,30(17):1304-1308.
[4] 中华医学会儿科学分会心血管学组,中华儿科杂志编辑委员会.病毒性心肌炎诊断标准<修订草案>[J].中华儿科杂志,2000,38(2):75.
[5] 国家中医药管理局.中医病证诊断疗效标准[S].南京:南京大学出版社,1994:78.
[6] 郑筱萸.中药新药临床研究指导原则(试行)[M].北京:中国医药科技出版社,2002:189-190.

相似文献/References:

[1]赵佐兴.五虎汤合葶苈大枣泻肺汤加减治疗新生儿支原体肺炎痰热闭肺证40例疗效观察[J].中医儿科杂志,2015,(03):18.
 ZHAO Zuoxing.Clinical curative effect of treatment with Wuhu Decoction combined with modified Tingli Dazao Xiefei Decoction treating neonatal mycoplasma pneumonia with phlegm heat obstructing lung syndrome[J].Journal of Pediatrics of Traditional Chinese Medicine,2015,(03):18.
[2]杜许芳,孟柳明,牛文泽,等.平喘止咳贴辅助治疗儿童支原体肺炎后咳嗽41例临床观察[J].中医儿科杂志,2016,(02):32.[doi:10.16840/j.issn1673-4297.2016.02.11]
 DU Xufang,MENG Liuming,NIU Wenze,et al.Clinic observation of 41 cases of Pingchuan Zhike Tie adjuvant therapy for pediatric mycoplasma pneumonia cough[J].Journal of Pediatrics of Traditional Chinese Medicine,2016,(03):32.[doi:10.16840/j.issn1673-4297.2016.02.11]
[3]杨配力,张存雪,苑修太.小儿支原体肺炎湿热致病论[J].中医儿科杂志,2016,(04):22.[doi:10.16840/j.issn1673-4297.2016.04.08]
 YANG Peili,ZHANG Cunxue,YUAN Xiutai.Pathogenic theory of damp heat in children with mycoplasma pneumonia[J].Journal of Pediatrics of Traditional Chinese Medicine,2016,(03):22.[doi:10.16840/j.issn1673-4297.2016.04.08]
[4]李静.加味麻杏石甘汤佐治小儿支原体肺炎48例临床观察[J].中医儿科杂志,2007,(03):40.
[5]吕玉霞,王玫,董彩凤,等.“抗支口服液”治疗小儿支原体肺炎168例疗效观察[J].中医儿科杂志,2007,(04):31.
 Lv Yuxia,Wang Mei,Dong Caifeng,et al.Oral “anti-bronchial syrup” for pediatric mycoplasma pneumonia: an observation of 168 cases[J].Journal of Pediatrics of Traditional Chinese Medicine,2007,(03):31.
[6]胡香玉,李君,杨静.小儿支原体肺炎的中西医结合治疗[J].中医儿科杂志,2007,(05):21.
 Hu Xiangyu,Li Jun,Yang Jing.Combine traditional Chinese and Western medicine for mycoplasmal pneumonia in children[J].Journal of Pediatrics of Traditional Chinese Medicine,2007,(03):21.
[7]李新丽.中西医结合治疗小儿支原体肺炎50例[J].中医儿科杂志,2008,(06):27.
[8]杜许芳,孟柳明,牛文泽,等.平喘止咳贴辅助治疗儿童支原体肺炎后咳嗽41例临床观察[J].中医儿科杂志,2016,(05):37.[doi:10.16840/j.issn1673-4297.2016.05.12]
 DU Xufang,MENG Liuming,NIU Wenze,et al.Clinical observation of 41 cases of children with cough after mycoplasma pneumonia treated by Pingchuan Zhike Tie[J].Journal of Pediatrics of Traditional Chinese Medicine,2016,(03):37.[doi:10.16840/j.issn1673-4297.2016.05.12]
[9]王陈裕,汪上信,蒋键波,等.中西医结合治疗儿童支原体肺炎46例临床观察[J].中医儿科杂志,2018,14(02):35.[doi:10.16840/j.issn1673-4297.2018.02.11]
 WANG Chenyu,WANG Shangxin,JIANG Jianbo,et al.Clinical observation on 46 cases of children with mycoplasma pneumonia treated with the combination of Chinese and Western medicine[J].Journal of Pediatrics of Traditional Chinese Medicine,2018,14(03):35.[doi:10.16840/j.issn1673-4297.2018.02.11]
[10]施霞静.热毒宁注射液辅助治疗儿童支原体肺炎32例临床观察[J].中医儿科杂志,2018,14(03):33.[doi:10.16840/j.issn1673-4297.2018.03.10]
 SHI Xiajing.Clinical observation on 32 cases of mycoplasma pneumonia in children treated with Reduning Injection as an adjuvant therapy[J].Journal of Pediatrics of Traditional Chinese Medicine,2018,14(03):33.[doi:10.16840/j.issn1673-4297.2018.03.10]

备注/Memo

备注/Memo:
基金项目:湖州市公益性技术应用研究项目(2017GYB55)。
作者简介:陆敏瑜(1982-),女,主治医师,医学学士,主要从事儿科临床诊疗工作。
更新日期/Last Update: 1900-01-01