[1]陈瑜.疏肝健脾汤辅助治疗小儿缺锌性厌食症肝脾不和型40例临床观察[J].中医儿科杂志,2019,15(03):48-51.[doi:10.16840/j.issn1673-4297.2019.03.16]
 CHEN Yu.Clinical observation on Shugan Jianpi Tang (疏肝健脾汤) in adjuvant treatment of 40 cases of child anorexia by zinc deficiency with disharmony between liver and spleen type[J].Journal of Pediatrics of Traditional Chinese Medicine,2019,15(03):48-51.[doi:10.16840/j.issn1673-4297.2019.03.16]
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疏肝健脾汤辅助治疗小儿缺锌性厌食症肝脾不和型40例临床观察
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《中医儿科杂志》[ISSN:/CN:62-1176/R]

卷:
15
期数:
2019年03期
页码:
48-51
栏目:
临床研究与报道
出版日期:
2019-05-25

文章信息/Info

Title:
Clinical observation on Shugan Jianpi Tang (疏肝健脾汤) in adjuvant treatment of 40 cases of child anorexia by zinc deficiency with disharmony between liver and spleen type
作者:
陈瑜
绍兴第二医院儿科, 浙江 绍兴 312000
Author(s):
CHEN Yu
Department of Pediatrics, Shaoxing the Second Hospital, Shaoxing, Zhejiang, 312000, China
关键词:
缺锌性厌食症儿童肝脾不和型疏肝健脾汤临床观察
Keywords:
anorexia by zinc deficiencychildrendisharmony between liver and spleen typeShugan Jianpi Tang (疏肝健脾汤)clinical observation
分类号:
R272.4
DOI:
10.16840/j.issn1673-4297.2019.03.16
摘要:
目的 观察疏肝健脾汤联合常规西药治疗小儿缺锌性厌食症肝脾不和型的临床疗效。方法 选取2015年10月至2017年12月于绍兴第二医院儿科就诊的缺锌性厌食症肝脾不和型患儿80例,按照随机数字表法分为对照组和治疗组,各40例。对照组予葡萄糖酸锌口服液、多潘立酮片和复合维生素片治疗,治疗组在对照组治疗方法的基础上联合疏肝健脾汤,并随症加减。治疗6周后统计2组的临床疗效、血清锌浓度、体质量变化情况以及不良反应发生情况。结果 2组治疗前血清锌浓度和体质量比较,差异均无统计学意义(P>0.05),具有可比性;治疗后2组上述指标较同组治疗前明显升高和增加,差异有统计学意义(P<0.05或P<0.01),且治疗组升高和增加更显著(P<0.05)。对照组总有效率为77.5%,治疗组为97.5%,2组比较,差异有统计学意义(P<0.01)。对照组总不良反应发生率为10.0%,治疗组为7.5%,2组比较,差异无统计学意义(P>0.05)。结论 疏肝健脾汤联合常规西药可显著提高小儿缺锌性厌食症肝脾不和型血清锌浓度、增加体质量,临床疗效显著,安全性高,值得临床推广应用。
Abstract:
Objective To observe the clinical efficacy of Shugan Jianpi Tang (疏肝健脾汤)combined with routine Western medicine in the treatment of child anorexia by zinc deficiency with disharmony between liver and spleen type.Methods Eighty cases of child anorexia by zinc deficiency with disharmony between liver and spleen type treated in department of pediatrics in Shaoxing the Second Hospital from October 2015 to December 2017 were chosen and divided into control group and treatment group according to random number table method,with 40 cases in each.The control group was given zinc gluconate oral liquid,domperidone tablets and multivitamin tablets,while the treatment group was combined with Shugan Jianpi Tang on the basis of the control group,modified with the symptoms.We kept statistics of the clinical efficacy,the changes of serum zinc concentration,body mass and incidence of adverse reactions between the two groups after treatment for 6 weeks.Results Before treatment,the difference was not statistically significant in serum zinc concentration and body mass between the two groups (P>0.05),and they were comparable.After treatment,the above indices of the two groups significantly rose or increased compared with the same group before treatment,and the difference was statistically significant (P<0.05 or P<0.01),moreover,the rise and increase of the treatment group was more significant (P<0.05).The total effective rate of the control group was 77.5%,that of the treatment group was 97.5%,there was statistically significant difference between the two groups (P<0.01).The total incidence of adverse reactions of the control group was 10.0%,that of the treatment group was 7.5%,there was no statistically significant difference between the two groups (P>0.05).Conclusion Shugan Jianpi Tang combined with routine Western medicine can significantly increase the serum zinc concentration,body mass of child anorexia by zinc deficiency with disharmony between liver and spleen type.It has significant clinical efficacy and high security,which is worthy of clinical promotion and application.

参考文献/References:

[1] 严芳,李兴堂.中药汤剂+推拿联合葡萄糖酸锌治疗小儿厌食症随机平行对照研究[J].实用中医内科杂志,2017,30(10):56-58.
[2] 吴俊生.厌食运脾膏联合小剂量锌制剂治疗小儿缺锌性厌食症临床研究[J].中医学报,2016,31(11):1803-1805.
[3] 国家中医药管理局.中医病症诊断疗效标准[S].北京:中国医药科技出版社,2012:93-94.
[4] 中华人民共和国卫生部.中药新药临床研究指导原则[M].北京:中国医药科技出版社,2012:134.
[5] 张松萍.健脾消化汤联合胃推拿法治疗小儿脾胃气虚型厌食症的临床观察[J].光明中医,2018,33(5):362-364.

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备注/Memo

备注/Memo:
作者简介:陈瑜(1988-),女,住院医师,医学学士,主要从事儿科临床诊疗工作。
更新日期/Last Update: 1900-01-01