[1]侯飞,宋杉.中西医结合治疗小儿功能性腹痛肝郁气滞证41例临床观察[J].中医儿科杂志,2019,15(03):58-61.[doi:10.16840/j.issn1673-4297.2019.03.19]
 HOU Fei,SONG Shan.Clinical observation on 41 cases of functional abdominal pain with depression of the liver-qi and stagnation of qi syndrome in children treated by combined traditional Chinese and Western medicine[J].Journal of Pediatrics of Traditional Chinese Medicine,2019,15(03):58-61.[doi:10.16840/j.issn1673-4297.2019.03.19]
点击复制

中西医结合治疗小儿功能性腹痛肝郁气滞证41例临床观察
分享到:

《中医儿科杂志》[ISSN:/CN:62-1176/R]

卷:
15
期数:
2019年03期
页码:
58-61
栏目:
临床研究与报道
出版日期:
2019-05-25

文章信息/Info

Title:
Clinical observation on 41 cases of functional abdominal pain with depression of the liver-qi and stagnation of qi syndrome in children treated by combined traditional Chinese and Western medicine
作者:
侯飞 宋杉
安吉县人民医院儿科, 浙江 安吉 313300
Author(s):
HOU Fei SONG Shan
Department of Pediatrics, Anji County the People's Hospital, Anji, Zhejiang, 313300, China
关键词:
功能性腹痛小儿肝郁气滞证中西医结合加味柴胡疏肝散胃肠激素临床观察
Keywords:
functional abdominal pain (FAP)childrendepression of the liver-qi and stagnation of qi syndromecombined traditional Chinese and Western medicinemodified Chaihu Shugan San (加味柴胡舒肝散)gastrointestinal hormonesclinical observation
分类号:
R256.33
DOI:
10.16840/j.issn1673-4297.2019.03.19
摘要:
目的 观察加味柴胡疏肝散联合西药治疗小儿功能性腹痛(FAP)肝郁气滞证的临床疗效。方法 选取2015年3月至2017年9月在安吉县人民医院儿科就诊的FAP肝郁气滞证患儿82例,按随机数字表法分为对照组和治疗组,各41例。对照组口服多潘立酮片和山莨菪碱片,治疗组在对照组治疗方法的基础上予加味柴胡疏肝散治疗,2组均治疗4周后统计疗效。结果 治疗前2组疼痛评分比较,差异无统计学意义(P>0.05),具有可比性。治疗后2组疼痛评分均较同组治疗前明显降低,经统计学分析,差异有统计学意义(P<0.01),且治疗组降低更显著(P<0.05)。治疗前2组中医证候积分比较,差异无统计学意义(P>0.05),具有可比性。治疗后2组中医证候积分均较同组治疗前明显降低,差异有统计学意义(P<0.01),且治疗组降低更显著(P<0.05)。治疗前2组胃动素(MOT)、胃泌素(GAS)、缩胆囊素(CCK)水平比较,差异均无统计学意义(P>0.05),具有可比性。治疗后2组MOT、GAS、CCK水平均较同组治疗前明显降低,差异有统计学意义(P<0.01),且治疗组降低更显著(P<0.05)。治疗组总不良反应发生率为9.7%,对照组为14.6%,2组比较,差异无统计学意义(P>0.05)。结论 加味柴胡疏肝散联合西药治疗FAP肝郁气滞证疗效显著,可明显减轻临床症状,改善胃肠功能,值得临床推广应用。
Abstract:
Objective To observe the clinical efficacy of modified Chaihu Shugan San (加味柴胡舒肝散) combined with Western medicine in the treatment of functional abdominal pain (FAP) with depression of the liver-qi and stagnation of qi syndrome in children.Methods Eighty-two cases of FAP with depression of the liver-qi and stagnation of qi syndrome admitted to department of pediatrics in Anji County the People's Hospital from March 2015 to September 2017 were chosen and divided into control group and treatment group according to random number table method, with 41 cases in each.The control group was given oral domperidone tablets and anisodamine tablets,while the treatment group was given modified Chaihu Shugan San on the basis of the control group.We kept statistics on clinical efficacy after the 2 groups were both treated for 4 weeks.Results Before treatment,there was no statistically significant difference in pain scores between the two groups (P>0.05),and they were comparable.After treatment,the pain scores of the two groups decreased significantly compared with the same group before treatment,and the difference was statistically significant (P<0.01),moreover,the treatment group decreased more significantly (P<0.05).Before treatment, there was no statistically significant difference in TCM symptom scores between the two groups (P>0.05),and they were comparable.After treatment,the TCM symptom scores of the two groups all decreased significantly compared with the same groups before treatment,and the difference was statistically significant (P<0.01),moreover,the treatment group decreased more significantly (P<0.05).Before treatment,there was no statistically significant difference in the levels of motilin (MOT),gastrin (GAS) and cholecystokinin (CCK) between the two groups (P>0.05),and they were comparable.After treatment, the levels of MOT,GAS and CCK of the two groups decreased significantly compared with the same groups before treatment,and the difference was statistically significant (P<0.01),moreover,the treatment group decreased more significantly (P<0.05).The total adverse reactions rate of the treatment group was 9.7%,that of the control group was 14.6%,and the difference was not statistically significant between the two groups (P>0.05).Conclusion Modified Chaihu Shugan San combined with Western medicine in the treatment of FAP with depression of the liver-qi and stagnation of qi syndrome in children has obtained significant curative effect,can significantly relieve clinical symptoms,and improve gastrointestinal function,which is worthy of clinical promotion and application.

参考文献/References:

[1] 席颖颖,杨硕平.腹痛宁颗粒治疗小儿功能性腹痛的临床研究[J].广州中医药大学学报,2018,11(2):237-241.
[2] 耿岚岚,刘明南,龙高,等.儿童功能性胃肠病罗马Ⅳ标准[J].中华儿科杂志,2017,55(1):4-14.
[3] 中华中医药学会.中医内科常见病诊疗指南·中医病证部分[M].北京:中国中医药出版社,2008:80.
[4] 严广斌.视觉模拟评分法[J].中华关节外科杂志(电子版),2014,8(2):34-34.
[5] 郭宇,苏晓兰,魏玮.功能性腹痛中西医诊疗进展与策略[J].中华中医药学刊,2016,34(5):1077-1080.
[6] 曾展华,龚志勇,蔡炼东.隔蒜灸足三里结合四磨汤治疗小儿功能性腹痛疗效分析[J].现代诊断与治疗,2015,26(18):4128-4129.
[7] SHEN CHUNRONG.The clinical observation and analysis of domperidone oral liquid combined with multienzyme tablets for the treatment of pediatric functional dyspepsia[J].Chinese Journal of Primary Medicine and Pharmacy,2015,8(16):2507-2508,2509.
[8] 王利玲,王远照,任昱,等.小儿化湿止痛汤治疗小儿功能性再发性腹痛69例[J].中国中医药科技,2015,22(3):341-342.
[9] 王安琪,吴坚芳.加味柴胡疏肝散联合黛力新治疗功能性腹痛综合征30例临床研究[J].江苏中医药,2018,50(6):39-41.
[10] 王英,郭鑫,宁春红,等.培菲康对功能性腹痛综合征患儿腹痛症状以及精神心理作用的影响[J].中国医药导报,2017,14(17):108-111.
[11] 赵力芳,贾鲲鹏.猴头菌提取物联合双歧杆菌四联活菌治疗小儿功能性消化不良[J].山西医药杂志,2016,45(12):1425-1427.

相似文献/References:

[1]辛晶.刘振寰教授治疗小儿屏气发作经验[J].中医儿科杂志,2015,(04):3.
 XIN Jing.Professor LIU Zhenhuan’s experience in treating infantile breath holding spell[J].Journal of Pediatrics of Traditional Chinese Medicine,2015,(03):3.
[2]潘馨,邵梦洁.穴位敷贴防治小儿感染后气道高反应咳嗽110例临床观察[J].中医儿科杂志,2015,(04):16.
 PAN Xin,SHAO Mengjie.Clinical observation of acupoint sticking in the treatment of 110 cases of children airway hyper reactivity cough after infection[J].Journal of Pediatrics of Traditional Chinese Medicine,2015,(03):16.
[3]谢敏,吕旭艳.黄芪颗粒治疗小儿反复呼吸道感染(营卫失和型)65例临床疗效分析[J].中医儿科杂志,2015,(04):20.
 XIE Min,LUE Xuyan.Clinical efficacy of Astragalus Particles in treating children recurrent respiratory tract infection of ying-wei disharmony type[J].Journal of Pediatrics of Traditional Chinese Medicine,2015,(03):20.
[4]江春燕,李成国,姚伟光.葶苈大枣泻肺汤加味外敷治疗小儿痰湿咳嗽200例临床观察[J].中医儿科杂志,2015,(04):28.
 JIANG Chunyan,LI Chengguo,YAO Weiguang.Clinical observation of external application of modified Tingli Dazao Xiefei Tang in the treatment of 200 cases of children with phlegm damp cough[J].Journal of Pediatrics of Traditional Chinese Medicine,2015,(03):28.
[5]汪永峰.中西医结合治疗小儿手足口病54例临床观察[J].中医儿科杂志,2015,(04):44.
 WANG Yongfeng.Clinical observation of integrated western and TCM medicine in treating 54 cases of children hand-foot-mouth disease[J].Journal of Pediatrics of Traditional Chinese Medicine,2015,(03):44.
[6]荣志云,张源,丛丽.小儿积滞发病的相关因素调查[J].中医儿科杂志,2015,(04):47.
 Rongzhiyun,Zhangyuan,Cong Li.Investigation on related factors of the pathogenesis of infantile dyspepsia[J].Journal of Pediatrics of Traditional Chinese Medicine,2015,(03):47.
[7]王良军.中西医结合治疗小儿幽门螺杆菌相关性胃炎73例临床观察[J].中医儿科杂志,2015,(04):53.
 WANG Liangjun.Clinical observation of TCM combined with western medicines in treating 73 cases of children Hp-associated gastritis[J].Journal of Pediatrics of Traditional Chinese Medicine,2015,(03):53.
[8]张梦桃,张映芬,李玉秀,等.脑瘫患儿睡眠障碍的护理[J].中医儿科杂志,2015,(04):70.
 ZHANG Mengtao,ZHANG Yingfen,LI Yuxiu,et al.Nursing care on sleep disorders of children with cerebral palsy[J].Journal of Pediatrics of Traditional Chinese Medicine,2015,(03):70.
[9]邬颖菲.苍苓止泻口服液辅助治疗小儿脾虚泻的临床疗效及护理措施[J].中医儿科杂志,2015,(04):73.
 WU Yingfei.Clinical efficacy and nursing care in the adjuvant treatment of spleen deficiency diarrhea in children with Cangling Zhixie Koufuye[J].Journal of Pediatrics of Traditional Chinese Medicine,2015,(03):73.
[10]张春玲.倪晓红主任医师论治小儿疳积经验[J].中医儿科杂志,2015,(02):10.
 ZHANG Chunling.Chief physician NI Xiaohong’s experience on the treatment of infantile malnutrition[J].Journal of Pediatrics of Traditional Chinese Medicine,2015,(03):10.
[11]师会娟,袁叶,高旅.小儿腹痛的中医临床研究进展[J].中医儿科杂志,2016,(03):83.[doi:10.16840/j.issn1673-4297.2016.03.30]
 SHI Huijuan,YUAN Ye,GAO Lv.Clinical research progress on TCM therapy for infantile abdominal pain[J].Journal of Pediatrics of Traditional Chinese Medicine,2016,(03):83.[doi:10.16840/j.issn1673-4297.2016.03.30]
[12]邵亚新,陈博宇,史睿.悦脾汤联合推拿疗法治疗儿童功能性腹痛脾胃虚寒证42例临床观察[J].中医儿科杂志,2017,(05):75.[doi:10.16840/j.issn1673-4297.2017.05.24]
 SHAO Yaxin,CHEN Boyu,SHI Rui.Clinical observation on 42 cases of children with functional abdominal (syndrome of deficient cold of spleen and stomach) treated with Yuepi Tang and Tuina[J].Journal of Pediatrics of Traditional Chinese Medicine,2017,(03):75.[doi:10.16840/j.issn1673-4297.2017.05.24]
[13]陈永辉,孙吉萍,麻建辉.小儿康颗粒治疗功能性腹痛42例临床观察[J].中医儿科杂志,2018,14(01):26.[doi:10.16840/j.issn1673-4297.2018.01.09]
 CHEN Yonghui,SUN Jiping,MA Jianhui.Clinical observation on 42 cases of functional abdominal pain treated with Xiao’erkang Granules[J].Journal of Pediatrics of Traditional Chinese Medicine,2018,14(03):26.[doi:10.16840/j.issn1673-4297.2018.01.09]

备注/Memo

备注/Memo:
作者简介:侯飞(1981-),男,主治医师,医学学士,主要从事儿科临床诊疗工作。
更新日期/Last Update: 1900-01-01